Discover transformative weight loss programs at Jolie Aesthetics & Wellness, featuring our once-weekly injectable treatments. Elevate your journey with other treatments in spa like MICC injections, Emsculpt sessions, and PCDC (Liquid Lipo), perfectly paired with Semaglutide and Tirzepatide for exceptional results.

MEDICAL WEIGHT LOSS

Semaglutide

  • Semaglutide is a GLP-1 receptor agonist—a medication originally developed to treat type 2 diabetes. It works by mimicking a natural hormone (GLP-1) that stimulates insulin release after meals, lowers blood sugar, and interacts with the brain to reduce hunger and food cravings. This dual-action effect helps support both blood sugar balance and weight loss.

    Unlike older appetite suppressants, Semaglutide works on a different pathway and has shown superior weight loss results in clinical trials.

    • Suppresses appetite by acting on the brain’s hunger centers

    • Slows gastric emptying, so you feel full longer

    • Regulates blood sugar and insulin levels to reduce fat storage

    • Enhances fat burning by keeping insulin and glucose levels in a steady, optimal range

    It’s part of a class of medications called incretin mimetics, which help your body respond better to meals—keeping energy steady while reducing hunger spikes.

  • Semaglutide is administered via a once-weekly subcutaneous injection. Your provider will start at a low dose and adjust gradually—no more frequently than every 4 weeks—to minimize side effects and help your body adapt.

    Common injection sites include:

    • Abdomen

    • Thigh

    • Upper arm

    Your provider will guide you on technique, site rotation, and storage.

    • Semaglutide is not a stimulant or quick-fix diet drug—it works best when combined with lifestyle changes.

    • You’ll need regular check-ins with your provider for dose adjustments and progress monitoring.

    • Common side effects may include nausea, constipation, or fatigue, especially when increasing your dose.

    • Not recommended during pregnancy or for individuals with a personal or family history of medullary thyroid carcinoma.

    We’ll review your health history thoroughly to ensure Semaglutide is the right fit for your weight loss journey.

Control hunger. Regain balance. Feel like you again.

Tirzepatide

  • Tirzepatide (brand name: Zepbound) is a once-weekly injection used to support weight loss in adults with obesity or overweight individuals who may also have conditions like type 2 diabetes, high blood pressure, sleep apnea, high cholesterol, or cardiovascular disease.

    It belongs to a unique class of medications that activate both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptors—offering dual-action metabolic support. By enhancing insulin release and suppressing glucagon (a hormone that raises blood sugar), it improves blood sugar control and reduces hunger signals.

  • Tirzepatide helps regulate blood sugar while supporting weight loss through multiple mechanisms:

    • Appetite Suppression: Mimics hormones that help control hunger and increase satiety

    • Slows Gastric Emptying: Keeps you feeling full longer, reducing calorie intake

    • Fat-Burning Support: Helps keep blood sugar low, allowing the body to more efficiently burn stored fat

    • Insulin Optimization: Enhances your body’s natural ability to release insulin when needed

    This makes Tirzepatide a comprehensive metabolic therapy—not just a weight loss injection.

  • Tirzepatide is injected once weekly under the skin (subcutaneously). Your provider will start at a low dose and gradually increase it—no more often than every 4 weeks—to minimize side effects and support your body’s adjustment.

    Injection sites include:

    • Abdomen

    • Thigh

    • Upper arm

    It’s recommended to rotate injection sites weekly for best results and comfort.

    • Effective Weight Reduction: Shown to produce significant weight loss in clinical trials

    • Appetite Control: Helps reduce cravings and supports mindful eating

    • Improved Body Composition: May reduce fat mass while preserving lean muscle

    • Cardiometabolic Health: Improves blood pressure, cholesterol, and blood sugar markers

    • Sustainable & Convenient: Once-weekly dosing helps with long-term adherence

    Tirzepatide supports more than just weight loss—it’s a strategic approach to improving metabolic health and long-term wellness.

    • Must be paired with healthy lifestyle changes for optimal results

    • Not recommended during pregnancy or for those with a history of medullary thyroid carcinoma

    • Side effects may include nausea, constipation, fatigue, or digestive changes

    • Regular follow-up is important to monitor dosing and progress

    Your provider will ensure that Tirzepatide is safe and appropriate based on your health history and goals.

Advanced GLP-1/GIP therapy for sustainable weight loss.

JOLIE WEIGHT LOSS SPECIALISTS

Located in Poughkeepsie location

Ellen Boothroyd, RN

Caitlin Giordano, NP

Kristen Lackaye, NP

Stephanie Motard, RN

Jenna Pascale, RN

Ali Rozzi, RN

Where Your Journey to Radiance Begins:

JOLIE AESTHETICS & WELLNESS